The Biopharmaceutics Classification System (BCS) is a scientific framework that is based on the. -testing (see Appendix II of the ASEAN Guidelines for the Conduct of Bioavailability and Bioequivalence Studies) or other suitable tests should be used to demonstrate. Solubility and dissolution of BCS Class II dug Spironolactone (Spl). (β-CD) was used as the principle carrier. The binary solid dispersion (SD).
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